Vaccinex Expands Access to ActivMAb Antigen Virus Technology

Lilu Anderson
Photo: Finoracle.net

Vaccinex Announces Creation of Eight New Antibody Discovery Agreements

Vaccinex, a biotechnology company specializing in Alzheimer’s disease and cancer treatments, has announced the creation of eight new antibody discovery agreements. These agreements will utilize Vaccinex’s proprietary ActivMAb platform, which allows for the selection of antibodies against challenging transmembrane protein targets.

President and CEO’s Perspective

The company’s President and CEO, Maurice Zauderer, emphasized the growing interest in their drug discovery technology. He believes this reflects a renewed focus on neglected biotech pipelines and a more optimistic market outlook. The ActivMAb platform stands out for its ability to target multi-pass membrane proteins, including G-protein-coupled receptors (GPCRs).

ActivMAb Platform Advantages

ActivMAb achieves targeting of complex proteins by expressing them on the membrane of a mammalian virus. This provides a more efficient and purified selection process compared to traditional methods.

Recent Milestones

ActivMAb has already achieved significant milestones, such as the selection of CHS-114, a fully human monoclonal antibody targeting CCR8 for cancer immunotherapy. This antibody is currently in clinical development.

Focus on Neurodegenerative Diseases and Cancer

Vaccinex continues to prioritize neurodegenerative diseases and cancer with its lead drug candidate, pepinemab, designed to block SEMA4D. Pepinemab is being studied in multiple clinical trials for Alzheimer’s Disease, Huntington’s disease, head and neck cancer in combination with KEYTRUDA®, and pancreatic adenocarcinoma in combination with BAVENCIO®.

Forward-Looking Statements

The company’s forward-looking statements express their intentions and expectations for the applications of the ActivMAb platform, the progress of their clinical development programs, and the commercial potential of their product candidates. Vaccinex acknowledges the potential risks and uncertainties that could impact these outcomes, including regulatory approvals and their reliance on their lead product candidate.

Analyst comment

Positive news. Vaccinex’s announcement of eight new antibody discovery agreements utilizing their ActivMAb platform reflects a growing interest in their technology and a more optimistic market outlook. The platform’s ability to target challenging transmembrane protein targets, including GPCRs, has already achieved significant milestones, such as the selection of a fully human monoclonal antibody for cancer immunotherapy. The company continues to prioritize neurodegenerative diseases and cancer, with their lead drug candidate in multiple clinical trials. However, potential risks and uncertainties, such as regulatory approvals, exist. Market response may be positive, with increased interest in Vaccinex and potential growth in the biotech sector.

Share This Article
Lilu Anderson is a technology writer and analyst with over 12 years of experience in the tech industry. A graduate of Stanford University with a degree in Computer Science, Lilu specializes in emerging technologies, software development, and cybersecurity. Her work has been published in renowned tech publications such as Wired, TechCrunch, and Ars Technica. Lilu’s articles are known for their detailed research, clear articulation, and insightful analysis, making them valuable to readers seeking reliable and up-to-date information on technology trends. She actively stays abreast of the latest advancements and regularly participates in industry conferences and tech meetups. With a strong reputation for expertise, authoritativeness, and trustworthiness, Lilu Anderson continues to deliver high-quality content that helps readers understand and navigate the fast-paced world of technology.